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Titlebook: Chromosomes Today; Volume 11 A. T. Sumner,A. C. Chandley Book 1993 Springer Science+Business Media Dordrecht 1993 Chromosome.DNA.Interphase

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From Chromosome Number to Chromosome Map: the contribution of human cytogenetics to genome mapping such as cancer material and samples of testis. Probably the first recorded description of human chromosomes was by Arnold in 1879 using mitotic cancer cells (Table 1). Hansemann in 1891 and Flemming in 1898 attempted to count the number of chromosomes in serial sections, obtaining crude estimates of approximately 24.
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Ribosomal genes and nucleolar morphology the fact that the genes for ribosomal RNA are not only transcribed but also processed and complexed with ribosomal proteins in nucleoli, rendering them morphologically different from the rest of the karyoplasm.
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Nucleolar proteins during mitosisddition proteins that are thought to provide structural support for the spatial arrangement of the rDNA and to play a role in the ordered translocation of pre-ribosomal subunits from their primary sites of assembly to their sites of translocation.
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Borelmengen und projektive Mengenongruent with the surface of the centromeric heterochromatin, and under some circumstances is not clearly resolved from the surrounding chromatin. In human the three layers are all about 35 nm thick and 430 nm in diameter (diameter estimated from Rieder (1982) assuming 20 microtubules per chromosome).
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Charakterisierungen und Konstruktionenribosomal proteins, nucleolar proteins and ribonucleoproteins (RNPs) is required for the nucleolar function, including RNA polymerase I, DNA topoisomerases, transcription factors, processing enzymes, 5S rRNA and U3, U8, U13 and U14 small nucleolar RNAs (snoRNAs) (..).
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https://doi.org/10.1007/BFb0069563rranged chromosome bands; cytogenetic analysis of non dividing cells that makes it unnecessary to obtain of metaphases and allows analysis of more cells than classical cytogenetics does. Consequently, applications of FISH now appear wider, allowing, for instance, studies on gene amplification and follow-up of patients in medical practice.
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