Titlebook: Cholesterol; Its Functions and Me Robert Bittman Book 1997 Springer Science+Business Media New York 1997 Lipid.development.metabolism.nervo

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Biological Implications of the Niemann-Pick C Mutation,fic molecular mechanisms. The relative paucity of experimental techniques available to study intracellular lipid trafficking has made the delineation of inherited metabolic defects particularly critical for delineating metabolic pathways of transport.

独轮车

Progesterone

Signaling Molecules Derived from the Cholesterol Biosynthetic Pathway,.., 1986; Porter and Spurgeon, 1981). These early studies led to the realization that the cyclic cholesterol molecule was derived from a polyisoprenoid, which in turn was shown to be composed of repeating five-carbon branched-chain building blocks derived from isopentenyl diphosphate (Rilling, 1985)

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,Coordinate Regulation of Cholesterol 7α-Hydroxylase and HMG-CoA Reductase in the Liver,HMGR), acyl cholesterol acyltransferase, cholesterol 7α-hydroxylase, and the LDL receptor (for a review, see Goldstein and Brown, 1990). The regulation of all these proteins is steroid dependent. This steroid-dependent regulation has been characterized in some detail at the gene level for HMG CoA sy

Multiple

Polyprenyl Diphosphate Synthases,standing of the process of cholesterol biosynthesis. The discovery of isopentenyl diphosphate (IPP), made independently by Lynen ..(1958) and Bloch ..(1959), opened the era of enzymatic studies on the fundamental chain elongation, which starts with the condensation between IPP and dimethylallyl diph

小步走路

Antifungal Sterol Biosynthesis Inhibitors,ed in 1146 ., titled “Antidotarium Niclai” (Grun, 1991). During the following millennium, there has been continued interest in drug discovery and application. However, only in the last fifty years have effective therapeutic agents for fungal disease been developed that exploit a fundamental differen

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biopsy