Titlebook: Chemical Protein Synthesis; Xuechen Li Book 2022 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Scie

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Xuechen LiIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts

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https://doi.org/10.1007/978-3-540-68583-8e of synthetic protein is greatly expanded. Proteoglycans are a class of sulfated glycoproteins widely distributed on the cell surface and in the extracellular matrix, which are extensively engaged in cellular communication events. Consisting of protein backbone and glycosaminoglycan(s) side chain,

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Defining the strategic businesseswith C-terminus salicylaldehyde esters and unprotected peptides with N-terminus serine/threonine or cysteine/penicillamine, which serve as powerful tools for cyclic peptide natural product and chemical protein synthesis. Herein, we introduce the preparation of C-terminal peptide salicylaldehyde este

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Development of strategic planningve compounds compared with normal peptides because they can enhance oral bioavailability, cell membrane permeability, and stability against enzymatic degradation. In our developed flow synthesis, a variety of .-methylated dipeptides is obtained in high yields without severe racemization from equival

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Corporate strategy development processwith WIP through its second SH3 domain (Nck-SH3.2). Recently we have developed a preventative antibacterial mechanism that safeguards intestinal cells by shutting down this intracellular signal through a site-selective covalent peptide–protein reaction, a new antibacterial strategy that acts on the