Titlebook: Chemical Mutagens; Principles and Metho Frederick J. Serres,Alexander Hollaender Book 1982 Springer Science+Business Media New York 1982 DN

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Nitrates and Nitrites: Ingestion, Pharmacodynamics, and Toxicology,not. It is hoped that some balance has been achieved in presentation of the most controversial points. Certainly, the reader is referred to the original literature that contains the data and theses on which the segments of this review were built. Nothing really new is presented in this review— just

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Short-Term Tests for Chemicals That Promote Aneuploidy,dividual having one, two, or a few chromosomes more or less than the basic number of the species in question.. The phenomenon of aneuploidy is thus exclusive to eukaryotes; although various aneu-ploid-like conditions have been described in bacteria and viruses, these are not normally considered to be aneuploids.

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The Human Leukocyte Test System,cytogenetic test system “closest to man.” (2) Some special characteristics of stimulable leukocytes in contrast to all other types of tissue-culture systems provide a unique cell system for the study of a variety of problems concerning mechanisms of induction of chromosomal aberrations.

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David R. Hayhurst,S. Hinduja,A W Labibhysical. This, of course, emanates from the fact that nearly all the genetic information in eukaryotes is encoded in a linear sequence in the microscopically visible mitotic, and meiotic, chromosomes, and any agent that is capable of disrupting this sequence will result in genetic changes either by

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Banh Tien Long,Kozo Ishizaki,Pham Duc Anerations, and mutations in somatic cells may be the possible cause of such diseases as cancer. and of advanced aging.. These health effects result in decreased fitness and life-span of and emotional stress on the affected person and in high cost to the society. Mutation monitoring of the human popul

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Bernard J. Jansen,Qingyuan Zhou,Jun Yecovery that many chemicals undergo various metabolic changes before they become biologically active.. Despite the great diversity of chemical structures, most carcinogens/mutagens appear to give rise to electrophilic derivatives (compounds with electron-deficient atoms), which then react with nucleo

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