| 书目名称 | Cerebral Signal Transduction | | 副标题 | From First to Fourth | | 编辑 | Maarten E. A. Reith | | 视频video | http://file.papertrans.cn/224/223320/223320.mp4 | | 概述 | Includes supplementary material: | | 丛书名称 | Contemporary Neuroscience | | 图书封面 |  | | 描述 | Since the pioneering discovery of cyclic AMP four decades ago, a multitude of signaling pathways have been uncovered in which an extracellular signal (first messenger) impacts the cell surface, thereby triggering a cascade that ultimately acts on the cell nucleus. In each cascade the first messenger gives rise to the appearance of a second messenger such as cyclic AMP, cyclic GMP, or diacylglycerol, which in turn triggers a third messenger, a fourth messenger, and so forth. Many advances in elucidating such pathways have been made, including efforts to link messenger molecules to brain processes operative in health or disease. However, the latter type of information, relating signaling pathways to brain function, is scattered across a variety of publication media, which makes it difficult to integrate the multiple roles of different signaling cascades into our understanding of brain function in health and disease. The primary aim of Cerebral Signal Transduction: From First to Fourth Messengers, therefore, is to offer a comprehensive picture of the recent advances made in the signaling field as it relates to neuronal and cere bral function. The current state of progress provides an | | 出版日期 | Book 2000 | | 关键词 | Alzheimer; alzheimer‘s disease; brain; depression; dopamine; memory; neurotransmitter; receptor | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-59259-019-3 | | isbn_softcover | 978-1-4684-9615-4 | | isbn_ebook | 978-1-59259-019-3 | | copyright | Springer Science+Business Media New York 2000 |
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