书目名称 | Cellular and Molecular Alterations in the Failing Human Heart | 编辑 | G. Hasenfuss,Ch. Holubarsch,N. R. Alpert | 视频video | | 图书封面 |  | 描述 | The myocardium in heart failure: Cellular and subcellular alterations in the failing human myocardium. H. Just Medizinische Universitatsklinik Freiburg i. Br., Innere Medizin III - Kardiologie, FRG The syndrome of heart failure continues to be a major challenge to clinicians and scientists. Incidence and mortality of the disease are high, the patient is disabled, and is permanently threatened by the high morbidity and mortality. The clinician faces a syndrome of complex pathophysiology. Multiple causes or underlying disorders of the heart have to be differentiated from heart failure itself, which often results in exceedingly difficult diagnoses. Likewise, prognostication meets with difficulties due to problems in separating influences of the underlying disease and the heart failure syndrome itself. In chronic refractory failure annual mortality may exceed 50%. If aortic stenosis or ischemic cardiomyopathy with main stem lesions are present, this percentage may be even higher. The situation becomes particularly threatening to the patient when the reduction in cardiac performance goes along with complex ventricular arrhythmias. Therapy has remained difficult and of limited effective | 出版日期 | Conference proceedings 1992 | 关键词 | cardiovascular; cardiovascular function; heart; heart failure; heart muscle; metabolism; pathophysiology; p | 版次 | 1 | doi | https://doi.org/10.1007/978-3-642-72474-9 | isbn_softcover | 978-3-642-72476-3 | isbn_ebook | 978-3-642-72474-9 | copyright | Dr. Dietrich Steinkopff Verlag GmbH & Co.KG, Darmstadt 1992 |
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