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Titlebook: Cellular and Biomolecular Mechanics and Mechanobiology; Amit Gefen Book 2011 Springer-Verlag Berlin Heidelberg 2011 Biorheology.Cell defor

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Normal and Abnormal Bone Healing,environment. These tools have helped to uncover findings that physical factors in the extracellular matrix can strongly affect important cell functions like proliferation, migration, differentiation, and survival. Here, we review the nanotechnologies that have been used for cellular adhesions and tr
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Injuries to the Axial Skeleton,lture models and new tools for probing them are needed for advancing our knowledge of mechanobiology. Cells physically interact with their surrounding extracellular matrix; they are able to sense the local stiffness, tension, and deformation within the matrix and, in turn, are able to remodel the ma
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Fall Prevention in the Elderly,f stresses as a result of these functional aspects, but the effects of these stresses on the individual cells are largely unknown. To understand the mechanical integrity of chondrocytes and how these properties change in response to various stimuli, mechanical testing systems for single cells have b
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Common Orthopaedic Emergencies,timately responsible for making breathing difficult. The past dozen years have led to major advances in our understanding of the rheology of the ASM and of the mechanical response to imposed stretch. This review covers the highly adaptable ability of cell function to be maintained over large length
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Fractured Pelvis and Acetabulum,sive utilization of different cellular mechanics experimental designs has been made over the years in order to provide better insight regarding the mechanical behavior of cells, and the mechanisms underlying the transduction of the applied loads into biological reactions. These experimental protocol
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Orthopedic Traumatology - A Resident‘s Guideder the influence of cytosol pressure. Blebbing is associated with cellular apoptosis and has been linked to diseased states such as cancer. Multiple phenomena at disparate scales occur during blebbing. At the molecular scale there are biochemical reactions governing actin polymerization, cross-link
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Orthopedic Traumatology - A Resident‘s Guide treated by mechanical ventilation. Recent clinical evidence suggests that it may be difficult to choose a ventilation protocol that completely eliminates the damaging mechanical forces experienced by the epithelium. In this chapter, we describe our research group’s use of both experimental and comp
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Trauma to the Upper Extremities,ate contractile forces and use this information to sense mechanical environment through interaction with material. In this sense, we consider that the cytoskeleton (CSK) of cells is mechanically prestressed. This prestress is generated by molecular motors that generate forces transmitted by the acti
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