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Titlebook: Cellular Therapies for Retinal Disease; A Strategic Approach Steven D. Schwartz,Aaron Nagiel,Robert Lanza Book 2017 Springer International

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发表于 2025-3-21 17:49:03 | 显示全部楼层 |阅读模式
书目名称Cellular Therapies for Retinal Disease
副标题A Strategic Approach
编辑Steven D. Schwartz,Aaron Nagiel,Robert Lanza
视频video
概述Drs. Schwartz and Lanza are two of the best known names in stem cell research and Dr. Schwartz is known particularly for clinical trials for stem cell therapies for ophthalmologic diseases.Focuses on
图书封面Titlebook: Cellular Therapies for Retinal Disease; A Strategic Approach Steven D. Schwartz,Aaron Nagiel,Robert Lanza Book 2017 Springer International
描述This book familiarizes the reader with the current landscape of cell-based therapies for the treatment of retinal disease, including diseases that affect the choriocapillaris, retinal pigment epithelium, photoreceptors, and retinal ganglion cells. Instead of utilizing a disease-centric approach to the topic, this book—edited by two world-renowned stem cell scientists—focuses on strategies for developing and transplanting the cells. This includes the creation of replacement cells, cell-based neuroprotection, and in vitro disease modeling and testing. The final chapters briefly review parallel approaches that do not directly utilize cellular transplantation..The use of cellular transplantation to treat retinal disease has recently become a viable and exciting therapeutic approach. The visibility of the retina and its laminar cellular architecture render it an ideal organ for the development of surgically delivered cellular therapies. Having an in-depth understanding ofthe current state of cell therapy for the eye is an essential first step toward utilizing similar approaches in other organs. Ophthalmologists, translational clinician-scientists, stem cell scientists, and researchers i
出版日期Book 2017
关键词Cell-based Neuroprotection; Cell Transplantation; Choriocapillaris; Pluripotent Stem Cells; Retinal Pigm
版次1
doihttps://doi.org/10.1007/978-3-319-49479-1
isbn_softcover978-3-319-84169-4
isbn_ebook978-3-319-49479-1
copyrightSpringer International Publishing AG 2017
The information of publication is updating

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发表于 2025-3-22 00:19:47 | 显示全部楼层
Scope of services to be outsourced, RPE monolayer and facilitate manipulation and subretinal implantation. An ideal scaffold should mimic the properties of the natural RPE substrate: Bruch’s membrane. It should have a similar thickness, flexibility, micro- and macromolecule permeability, and the ability to promote survival, polarity,
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Book 2017t of surgically delivered cellular therapies. Having an in-depth understanding ofthe current state of cell therapy for the eye is an essential first step toward utilizing similar approaches in other organs. Ophthalmologists, translational clinician-scientists, stem cell scientists, and researchers i
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Subretinal Delivery of Cells via the Suprachoroidal Space: Janssen Trialtes to the subretinal space. After considering a number of potential techniques, they developed a novel approach using the suprachoroidal space as a conduit to the posterior pole. This approach involves the creation of a sclerotomy, introduction of a specialized cannula into the suprachoroidal space
发表于 2025-3-23 07:48:56 | 显示全部楼层
Retinal Organoids: An Emerging Technology for Retinal Disease Research and Therapyoes not reproduce that of late fetal development. However, studies to date suggest that immature photoreceptor or retinal ganglion cells, roughly those of mid-gestation, function best for transplantation. This developmental stage appears to be well reproduced in vitro, and therefore the PSC-derived
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