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Titlebook: Cell death in the morphogenesis and teratogenesis of the heart; Tomas Pexieder Book 1975 The Editor(s) (if applicable) and The Author(s),

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书目名称Cell death in the morphogenesis and teratogenesis of the heart
编辑Tomas Pexieder
视频video
丛书名称Advances in Anatomy, Embryology and Cell Biology
图书封面Titlebook: Cell death in the morphogenesis and teratogenesis of the heart;  Tomas Pexieder Book 1975 The Editor(s) (if applicable) and The Author(s),
描述In spite of the continuing progress of research in the fields of cellular and molecular biology, which has oriented many embryologists towards molecular biology, no concrete explanation of morphogenesis has yet been found. The present state of knowledge of heart development is characterized by an enormous discrepancy between the qualitative descriptions of what happens on the organ level and the more or less quantitative information on subcellular and molecular events. It is generally not understood how cells form tissues and how tissues generate particular forms of an organ. In an attempt to fill the gaps we systematically studied in the period 1968 to 1973 one of the general but rather neglected morphogenetic mechanisms which integrates cells into tissues and organs-cell death. Only a small part of our research on cell death in the development of chick, rat and human embryo hearts has as yet been published in extenso. Most of it has been communicated in papers delivered at different scientific meetings. We would like to use the opportunity offered by Advances to present a syn­ thesis and integrative review of our results. In this way the actual period of discovery of the existenc
出版日期Book 1975
关键词biology; cell; cell death; development; embryo; heart; molecular biology; morphogenesis; morphology; tissue
版次1
doihttps://doi.org/10.1007/978-3-642-66142-6
isbn_softcover978-3-540-07270-6
isbn_ebook978-3-642-66142-6Series ISSN 0301-5556 Series E-ISSN 2192-7065
issn_series 0301-5556
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
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Introduction,y, cell death and necrosis. For him the death of cells is a consequence of a pathogene action (La Via and Hill, 1971). But there are in almost every living organism thousands of cells that die spontaneously by a process which is called with some ambiguity “physiological” or “spontaneous” cell death.
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Topography of Cell Death in the Chick Embryo Heart,ell as of any other embryonic organs reveals the random presence of isolated dead and dying cells with the morphology described in chapter III. We have named this “background cell death” (Pexieder, 1971c, 1972d). A definition and extensive discussion of “background cell death” together with the desc
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Comparative Topography of Cell Death Zones in Rat and Human Embryo Hearts,lue of these observations for mammalian and especially human embryos ? Initial comparisons of the occurrence of cell death foci by Glücksmann (1951) have shown that these can be found in different vertebrate species. The research report by Menkes, Deleanu and lilies (1965) has shown that at least in
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Supravital Nile Blue Sulphate Staining in the Cell Death Studies,37; Bieling, 1937). Neutral red (Ries, 1937), trypan blue (Williams, 1950; Weimar, 1959), lissamine green (Holmberg, 1961), methylene blue (Saunders .., 1962; Koenig, 1965), Nile blue sulphate (Saunders .., 1962; Center, 1970), eosin (Geczy and Baumgartner, 1970) and nigrosin (Kaltenbach .., 1958) w
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Cell Death and the Morphogenesis of the Heart,concentrated on the analysis of the assymmetry and the primary bending (looping) of the primitive heart tube (Orts-Llorca, 1964, 1970; De Haan, 1967; Lepori, 1967; Orts-Llorca and Gil, 1967; Renaud and Le Douarin, 1968 a, b; Stalsberg, 1969 a, 1970; Castro-Quezada .., 1972; Manasek, 1972; Manasek an
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