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Titlebook: Cartilage and Osteoarthritis; Frédéric Ceuninck,Massimo Sabatini,Philippe Pastou Book 2004 Humana Press 2004 Arthritis.bone.cartilage.comp

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书目名称Cartilage and Osteoarthritis
编辑Frédéric Ceuninck,Massimo Sabatini,Philippe Pastou
视频video
概述Includes supplementary material:
丛书名称Methods in Molecular Medicine
图书封面Titlebook: Cartilage and Osteoarthritis;  Frédéric Ceuninck,Massimo Sabatini,Philippe Pastou Book 2004 Humana Press 2004 Arthritis.bone.cartilage.comp
描述An indispensable collection of updated classical and emerging techniques that promise to add critical knowledge to our understanding of cartilage metabolism in health and disease. Volume 1: Cellular and Molecular Tools describes proven molecular and cellular techniques for the in vitro study of normal and osteoarthritic cartilage through biochemical, biomolecular, immunological, and physical approaches, with emphasis on the genetic manipulation of cells. Volume 2: Structure and In Vivo Analysis, offers cutting-edge procedures for the study-at the tissue level-of turnover, structure, and functioning of normal and diseased articular cartilage by invasive and noninvasive means. Comprehensive and up-to-date, the two volumes of Cartilage and Osteoarthritis provide researchers and bench scientists with readily reproducible protocols for new experiments to understand-from the cellular to the animal level-the pathophysiology of cartilage and to discover molecular targets for pharmacological intervention.
出版日期Book 2004
关键词Arthritis; bone; cartilage; computed tomography; computed tomography (CT); imaging; joint; metabolism; osteo
版次1
doihttps://doi.org/10.1385/1592598218
isbn_softcover978-1-61737-606-1
isbn_ebook978-1-59259-821-2Series ISSN 1543-1894 Series E-ISSN 1940-6037
issn_series 1543-1894
copyrightHumana Press 2004
The information of publication is updating

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Histological and Immunohistological Studies on Cartilage,ogical procedures. This chapter documents some of the protocols we have developed in our laboratories for the histological and immunohistochemical evaluation of extracellular-matrix components in normal and pathological articular cartilage. Illustrative examples are provided of specimens from an ovi
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Histochemical Visualization of the Cartilage Hyaladherins Using a Biotinylated Hyaluronan Oligosacc HA (bHA) oligosaccharide bioaffinity probe. The bHA oligosaccharide probe was prepared by partial digestion of HA with ovine testicular hyaluronidase, and the oligosaccharides were labeled with biotin hydrazide and purified by a combination of aggrecan G1 domain and avidin affinity chromatography.
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Mechanical Characterization of Native and Tissue-Engineered Cartilage, another, all the while being loaded and unloaded. The durability of the tissue also makes for an impressive material to study. However, when cartilage is damaged or diseased, the tissue has little capacity to repair itself. The goal of cell-based repair strategies to replace damaged or diseased tis
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