Titlebook: Cardiovascular Safety in Drug Development and Therapeutic Use; New Methodologies an J. Rick Turner,Dilip R. Karnad,Snehal Kothari Book 2017

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Demonstration of a matrix Laboratory, the focus moves to assessments of safety. As will be seen in the first part of this chapter, general safety assessments are conducted quite differently from those for efficacy, in that descriptive statistics are used as opposed to hypothesis testing. However, in the domain of cardiovascular safety,

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https://doi.org/10.1007/BFb0075155ne-Gill et al. 2014; Kennelly and Esaian 2013), our attention falls on increases. As was noted in Sect. ., high blood pressure is authoritative regarded as the greatest threat to the global burden of disease (Horton 2013; Das and Samarasekera 2013; Lim et al. 2013). As hypertension has been studied

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Cardiovascular Structure, Function, and Pathophysiology each case, attention falls first on the heart, since multiple subsequent chapters focus on proarrhythmia. Nonetheless, discussions of the cardiovascular system are also pertinent to topics addressed later in the book.