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Titlebook: Cardiac Valve Allografts; Science and Practice Magdi H. Yacoub (Professor and Director),A. Charle Conference proceedings 1997 Springer-Verl

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楼主: 倒钩
发表于 2025-3-30 09:39:19 | 显示全部楼层
Homograft viability, assessment and significanceic), human cardiac allografts are considered to be superior in haemodynamic performance, relatively resistant to endocarditis, have minimal thromboembolic complications and do not require anticoagulation (1–4). However, the main disadvantages of human cardiac allografts over prosthetic valves are th
发表于 2025-3-30 16:11:52 | 显示全部楼层
Human heart cold ischemia and its effect on post-cryopreservation viability of heart valves Cellular viability and function were assessed through measurement of protein synthesis, ribonucleic acid synthesis, and glucose phosphorylation. Cold ischemia times varied from 24 to 113 h before processing and cryopreservation. The results show that valve leaflet cellular functions could be detect
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Effects of storage temperature and fetal calf serum on the endothelium of porcine aortic valves: Funemperatures for preserving long-term endothelial function of porcine aortic valves, different storage temperatures and different periods of time were investigated. Fresh valves were either a) stored at 4 °C with or without 10% fetal calf serum (FCS) supplement, for 1, 2,4, 7, 14, 21, and 28 days. b)
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发表于 2025-3-31 01:10:10 | 显示全部楼层
The anatomic and physiological properties of the semilunar valves pulmonary circulations has become a standard procedure in patients with congenital and acquired heart valve diseases. Currently, the pulmonary autograft and allograft valves, following their clinical use in 1967 and 1983 by Ross as valve substitutes in the systemic and pulmonary circulation, respec
发表于 2025-3-31 06:43:26 | 显示全部楼层
Antigenicity of human cardiac valve allografts in vitrohuman leukocyte antigens (HLA) and immunosuppressive therapy is not routinely given to valve recipients. Therefore, immunologic activity of the valve acceptor against allogeneic tissue may play a role in valve destruction. In this study, we examined the immunogenicity of human donor valves in vitro.
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Immunology of homograft valves a superior long-term performance compared with grafts stored at 4°C (14). In contrast to these fresh-wet-stored valves, it seems that cryopreserved grafts keep their viability undamaged, allowing storage at − 196 °C for years of these rare and precious prostheses (12).
发表于 2025-3-31 15:46:32 | 显示全部楼层
Immunogenicity of human cardiac valve allograftsssue has become an accepted treatment of organ and tissue failure. Lam et al. introduced the concept of allograft heart valve replacement in 1952 (9). Today, the use of allogeneic material for heart valve replacement is an accepted clinical treatment option along with mechanical valve prostheses, wh
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The allograft valve in aortic valve replacement and in transplanted patientsdescending aorta and attempted, although without success, to implant valve allografts in the same position (reviewed in 35). Five years later, Murray, following the experimental work by Lam and colleages (20), succeeded where Hufnagel had failed, when by placing an allograft in the descending aorta
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