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Titlebook: Cardiac Regeneration; Masaki Ieda,Wolfram-Hubertus Zimmermann Book 2017 Springer International Publishing AG 2017 fibroblast.heart repair.

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Miscellaneous Properties and Results,t of immune suppression and the strategic approach to optimize immune suppression without subjecting the target patient population to an unacceptable risk. This chapter summarizes the current state of tissue-engineered heart repair with a special emphasis on knowledge gained from in vitro and in viv
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Past and Future of Cell-Based Heart Repair, the adult human heart are in constant development in both the experimental and clinical arenas. Although stem cell therapies remain controversial, cell-based heart repair is a promising approach toward regenerating the adult human heart. Experience with cell therapy has resulted in several importan
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Differentiation and Use of Induced Pluripotent Stem Cells for Cardiovascular Therapy and Tissue Engperties suggest that hiPSC products may be an ideal source of cells for medical science and therapeutic use. Here, we discuss recent advancements in techniques for differentiating hiPSCs into cardiomyocytes, endothelial cells, and smooth muscle cells and in the use of hiPSC-derived cells for cardiov
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Application of the Suspension Culture System for Scale-Up Manufacture of hPSCs and hPSC-Derived Caren a bottleneck for the progress of cell therapy for heart diseases. The adherent cell culture platforms have been well developed for hPSC maintenance and cardiac differentiation. However, the two-dimensional culture system is limited by its scalability, hindering its application for scale-up cell p
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State of the Art in Cardiomyocyte Transplantation,action (e.g., by promoting angiogenesis or attenuating adverse ventricular remodeling), cardiomyocyte transplantation aims to repopulate the infarct scar with functionally integrated new myocardium that will directly contribute to contractile function. Early proof of concept for this “direct remuscu
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