Titlebook: Cardiac Cell and Gene Transfer; Joseph M. Metzger (Director) Book 2003 Humana Press 2003

相互影响

Dual Vector Expansion of the Recombinant AAV Packaging Capacityuch as naked or liposome-complexed DNA. At the same time, rAAV also displays the least inflammatory response in comparison with other viral vectors such as adenovirus and herpes simplex virus (.). Regulated myocardial transgene expression has also been demonstrated with an AAV vector containing glucocorticoid response elements in rat heart (.).

制造

Cell Therapy in the Heartvery. This review details techniques for the purification of commonly investigated cell grafts, including skeletal myoblasts and mesenchymal stem cells, and the methods to deliver these grafts to the myocardium of laboratory animals.

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Insensate

Methods in Molecular Biologyhttp://image.papertrans.cn/c/image/221746.jpg

实施生效

Alexey Pavlov,Nathan van de Wouwity of the vector being delivered. Purity in this case is defined both from the standpoint of genetic homogeneity, and from the absence of any toxic elements that may jeopardize cellular homeostasis and/or virion-cell receptor interactions. The evolution from plasmid to recombinant adenoviral vector

allude

vibrant

Dennis J. W. Belleter,Kristin Y. Pettersend on the success of numerous proof of principal gene transfer experiments. Stable high-level expression has been achieved following a variety of delivery methods (direct cardiac muscle injection, coronary vascular or carotid artery infection) and in a wide range of animal models from rodents to pigs

CESS

Alexey Pavlov,Nathan van de Wouwf foreign DNA into cardiac myocytes is of potential value for therapeutic applications (.,.) and also offers an experimental approach to investigate the roles of individual genes in cardiovascular pathophysiology. Both efficient delivery and long-term expression of transduced genes is required befor

Osmosis

https://doi.org/10.1007/978-1-4757-3108-8enerative capacity of adult cardiac tissue and the lack of a resident cardiac progenitor cell equivalent to the skeletal myoblast, the transplantation of myogenic cells into the myocardium has been investigated as a novel mechanism to repair damaged and dysfunctional myocardium. For maximal impact o

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https://doi.org/10.1007/978-3-319-67140-6types of heart disease. The two primary applications of cellular transplantation are to generate new functional myocardium and to deliver therapeutic agents such as growth factors into diseased hearts. Cardiac cellular transplantation experiments have been performed using different cell types, inclu