Titlebook: Capillary Electrophoresis of Proteins and Peptides; Methods and Protocol Nguyet Thuy Tran,Myriam Taverna Book 2016 Springer Science+Busines

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Affinity Monolith-Integrated Microchips for Protein Purification and Concentration,ion were prepared by direct in-situ photopolymerization of glycidyl methacrylate and ethylene glycol dimethacrylate in porogenic solvents consisting of 1-dodecanol and cyclohexanol. By integrating affinity monoliths onto a microfluidic system, targeted biomolecules can be captured and retained on af

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Analysis of Somatropin by Double-Injection Capillary-Zone Electrophoresis in Polybrene/Chondroitin rophoresis in double-injection mode using polybrene/chondroitin sulfate A double-coated capillaries. Modification of the capillary wall eliminates protein-wall interactions which results in improved accuracy and precision of the determinations. In the double-injection mode two somatropin samples are

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Separation of Recombinant Therapeutic Proteins Using Capillary Gel Electrophoresis and Capillary Is on two techniques, capillary gel electrophoresis (CGE) and capillary isoelectric focusing (cIEF). CGE is essentially gel electrophoresis, performed in a capillary, where a hydrogel is used as a sieving matrix to separate proteins or peptides based on size. cIEF separates proteins or peptides based

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Characterization of Chemical and Physical Modifications of Human Serum Albumin by Capillary Zone Elchange or reduce their biological activity. Therefore, it is important to have analytical methodologies that are able to reliably detect, characterize, and quantify degradation products in formulations. Capillary Zone Electrophoresis (CZE) is very well suited for the analysis of proteins due to its

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Capillary Electrophoresis Method for the Assessment of Erythropoiesis-Stimulating Agents in Final Fch as isoelectric point or molecular weight, or in terms of purity/heterogeneity for the presence of charge or size variants. In glycoproteins the heterogeneity occurring as a consequence of variable amounts of terminal sialic acid residues on glycan moieties can be detected by CE. As such, a capill

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Quality Control of Therapeutic Monoclonal Antibodies at the Hospital After Their Compounding and BeHere we describe a highly reproducible CZE method, relying on a cationic coating allowing separation and identification of a complex mixture of four compounded mAbs widely used in cancer therapy (cetuximab, rituximab, bevacizumab, and trastuzumab).

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