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Titlebook: Cancer: Cell Structures, Carcinogens and Genomic Instability; Leon P. Bignold Book 2006 Birkhäuser Basel 2006 angiogenesis.animals.apoptos

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书目名称Cancer: Cell Structures, Carcinogens and Genomic Instability
编辑Leon P. Bignold
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概述A concise compilation of current knowledge about tumor morphological abnormality.Provides insight into molecular mechanisms of carcinogenesis.Presents new targets for medical intervention
丛书名称Experientia Supplementum
图书封面Titlebook: Cancer: Cell Structures, Carcinogens and Genomic Instability;  Leon P. Bignold Book 2006 Birkhäuser Basel 2006 angiogenesis.animals.apoptos
描述This volume began with an invitation from the publishers to edit a volume of EXS on Cancer. This invitation undoubtedly derived from my articles in Cellular and Molecular Life Sciences in 2002 and 2003 on the relationships between the morphology, aetiology and pathogenesis of tumours, especially in relation to genetic instability. After many years of teaching the theories of c- cer in undergraduate medical school courses, it seemed to me that the variably chaotic histopathologic features of tumours parallel in some way, the variably unstable genomes of tumour cells, which were being discovered in the 1990s. Thus the title of the volume has come to include morphology, carcinogenesis and genetic instability. The invitation came while I was working with Herrn Dr. med. Hubertus Jersmann (MD Düsseldorf, PhD, now Senior Lecturer in Medicine of the University of Adelaide) and Professor Brian Coghlan (Emeritus Professor of German, the University of Adelaide), on the work of the nineteenth century cancer pathologists, especially David Paul von Hansemann (1858–1920). With the delivery of the manuscripts from the authors of the chapters, it became obvious that a background chapter for the vol
出版日期Book 2006
关键词angiogenesis; animals; apoptosis; behavior; cancer; cancer research; carcinogenesis; cell; gene expression; g
版次1
doihttps://doi.org/10.1007/3-7643-7378-4
isbn_ebook978-3-7643-7378-8Series ISSN 1664-431X Series E-ISSN 2504-3692
issn_series 1664-431X
copyrightBirkhäuser Basel 2006
The information of publication is updating

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The mode of action of organic carcinogens on cellular structures, important molecular mechanisms in chemical carcinogenesis, the role of the enzymes involved in bioactivation, the target gene structures of some ultimate carcinogenic metabolites, and implications for human cancer risk assessment are discussed.
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Genetic and environmental factors in hereditary predisposition to tumors: a conceptual overview,art of the study of problems in carcinogenesis; e.g., multistep carcinogenesis, cancer prevention and the development of the therapeutic treatments that can be translated to human patients, as well as how environmental factors interact with cancer susceptibility gene(s).
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1664-431X s.Presents new targets for medical interventionThis volume began with an invitation from the publishers to edit a volume of EXS on Cancer. This invitation undoubtedly derived from my articles in Cellular and Molecular Life Sciences in 2002 and 2003 on the relationships between the morphology, aetiol
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