| 书目名称 | Cancer Drug Delivery Systems Based on the Tumor Microenvironment | | 编辑 | Yasuhiro Matsumura,David Tarin | | 视频video | | | 概述 | Introduces drug design based on cancer pathophysiology.Describes the benefits of a drug delivery system that integrates nanotechnology, biotechnology, and nano biotechnology.Explains the new cancer dr | | 图书封面 |  | | 描述 | .This book proposes the importance of new systems of drug design and delivery based on cancer pathophysiology in addition to cancer molecular and cellular biology. The current studies based on molecular and cellular biology while ignoring pathophysiology and pharmacology may be leading the development of antitumor drugs in the wrong direction and wasting a lot of money. Although there have been numerous reports of genetic and phenotypic changes in tumors, a large body of pathological and clinical evidence supports the conclusion that there are no pivotal changes in tumor cells that distinguish them consistently and reliably from normal dividing cells. Unlike using antibiotics against bacterial infection, therefore, anticancer agents (ACAs) need to be delivered selectively to tumor tissues and should be kept there long enough to reproduce the concentrations they reach in the Petri dish, which is a closed space where the cytocidal effects of any anticancer agents (ACAs) including molecular targeting agents are very strong. In the body, however, administered ACAs are cleared with the passage of time. Furthermore, most human cancers possess abundant stroma that hinders the penetration | | 出版日期 | Book 2019 | | 关键词 | Anticancer Agents; Cancer Biology; Cancer Therapy; Cancer pathphysiology; Nanobiotechonology | | 版次 | 1 | | doi | https://doi.org/10.1007/978-4-431-56880-3 | | isbn_ebook | 978-4-431-56880-3 | | copyright | Springer Japan KK, part of Springer Nature 2019 |
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发表于 2025-3-21 17:39:25
