Titlebook: Cancer Cell Signaling; Methods and Protocol David M. Terrian Book 2003 Humana Press 2003

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Protein Tyrosine Kinase and Phosphatase Expression Profiling in Human Cancersrotein tyrosine kinase/phosphatase molecules from cancer cells by reverse-transcription polymerase-chain-reaction. An improved profiling approach (RAGE) was also described by utilizing restriction enzyme digestion and electrophoresis for quick and efficient kinase/phosphatase profiling.

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Regressive Phenomena: Refining Connectionsctivity and halt cell-cycle progression. In this chapter, we present three methods that have been utilized to monitor the antimitogenic action exerted by tumor suppressors. Tumor suppressor function can be demonstrated by colony formation assays and acquisition of the flat-cell phenotype. Because of

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Neuroscience in the 21st Century resistance. In neuroblastomas there is evidence that acquired drug resistance may be associated with altered response to growth factor signals. The ubiquitous mitogen-activated protein kinase (MAPk) cascade, which transmits growth factor signals from the cell membrane to the nucleus, provides a pri

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