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Titlebook: CNS Cancer; Models, Markers, Pro Erwin G. Meir Book 2009 Humana Press 2009 CNS.Nervous System.angiogenesis.brain.brain tumor.brain tumors.c

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Neuro-oncogenesis Induced by Nitroso Compounds in Rodents and Strain-Specific Genetic Modifiers of Prodents. They induce tumors of the central (CNS) and peripheral nervous system (PNS), which are similar to their human counterparts. The neuro-oncogenic effect of both chemicals depends on the dose, the rodent species, the strain, and the developmental stage at exposure. Neuro-oncogenesis induced by
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The PTEN/PI3 Kinase Pathway in Human Gliomalls. Ten years later, the . gene was isolated by its deletion in a large proportion of human cancers, including glioblastoma. These two areas of research converged when it was shown that PTEN dephosphorylated the lipid product of PI3K activity, phosphatidylinositol (3,4,5) trisphosphate, or PIP3. Fu
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