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Titlebook: Axon Growth and Guidance; Dominique Bagnard Book 2007 The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer

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Membrane Lipid Rafts and Their Role in Axon Guidance,r spatial and temporal control of guidance signaling by extracellular cues. In addition, lipid rafts may also function in other aspects of axonal growth and guidance, including spatial and temporal regulation of adhesion, cytoskeletal dynamics, and growth cone motility. Further elucidating how membr
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Rebecca J. Gordon,Michael A. Levineacellular cues which are diffusible, or bound to cell membranes or extracellular matrix. The exact molecular mechanisms through which these extracellular signals are integrated by the growing axon, are not yet well defined. However, it is widely accepted that most, if not all, signaling cascades tri
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Familial Isolated Hypoparathyroidismed in mammals, in addition to two GPI-anchored membrane proteins, netrin-G1 and G2. Orthologues of netrin-1 play a highly conserved role as guidance cues at the midline of the developing CNS of vertebrates and some bilaterally symmetric invertebrates. In vertebrates, floor plate cells at the ventral
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Michael Mannstadt MD,John T. Potts Jr. MDually described as a step-by-step mechanism of growth recruiting several guidance cues with attractive and repulsive properties. Among these signals, the semaphorins define a large family of more than 20 members divided into eight classes according to their phylogenic relationship and the existence
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https://doi.org/10.1007/b138429al nervous system by midline glia cells .–.. Slit homologues have since been found in .. and many vertebrate species, from amphibians, . fishes, . birds .–. to mammals ..–.. A single . was isolated in invertebrates, whereas there are three . genes (.) in mammals, that have around 60% homology .. All
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https://doi.org/10.1007/b138429ntly, molecular evidence suggests that neurotrophic factors and axon guidance molecules reglate the same signalling pathways in neurons. Yet only a few critical studies have tested a possible role for neurotrophic factors as guidance molecules in vivo. In this chapter I review the evidence for and a
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