Titlebook: Autophagosome and Phagosome; Vojo Deretic Book 2008 Humana Press 2008 Amino acid.Autolysosomes.Autophagy.Fluorescence Microscopy.Organelle

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Clearance of Mutant Aggregate-Prone Proteins by Autophagy,s or proteinopathies. We have shown that autophagy, a cytosolic, non-specific bulk degradation system, is an important clearance route for many cytosolic toxic, aggregate-prone proteins, like mutant huntingtin and mutant .-synucleins. Induction of autophagy enhances the clearance of both soluble and

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Localization and MHC Class II Presentation of Antigens Targeted for Macroautophagy,MHC class II presentation of potential vaccine antigens, we have developed a method to target antigens for autophagic degradation via fusion to the Atg8/LC3 protein: Atg8/LC3 is specifically incorporated into autophagosomes via coupling to phosphatidylethanolamine, and subsequently degraded in MHC c

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https://doi.org/10.1007/978-981-15-5709-5terior, respectively. In their most primordial form, both processes are involved in cellular metabolism and feeding, supplying cells with externally obtained particulate nutrients or using portions of cell’s own cytoplasm to generate essential nutrients and energy at times of starvation. Although au

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