Titlebook: Atypical Elements in Drug Design; Jacob Schwarz Book 2016 Springer International Publishing Switzerland 2016 Drug Design.Silicon Mimics.Un

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GIS for Health and the Environmented. After the discovery of selenium as a key component of many proteins, significant research efforts have been focused on its therapeutic and nutritional potentials and possible impacts on human and animal health. To date, 25 selenoprotein genes have been identified in humans and animals, where sel

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Atypical Elements in Drug Design978-3-319-27742-4Series ISSN 1862-2461 Series E-ISSN 1862-247X

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978-3-319-80205-3Springer International Publishing Switzerland 2016

Foreknowledge

The Future of Boron in Medicinal Chemistry: Therapeutic and Diagnostic Applications,n’s strong Lewis acidity and ability to undergo fission under neutron bombardment form the foundation for boron-containing compounds to be developed as inhibitors of hydrolytic enzymes, chemosensors and artificial receptors for carbohydrates and other Lewis bases, and boron neutron capture agents. A

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Drug Design Based on the Carbon/Silicon Switch Strategy,egic replacement of a carbon atom with a silicon atom (sila-substitution) within a well-known drug, with the rest of the molecule being identical, is one of the methods that are currently used for the design and development of new silicon-based drugs. Some of the fundamental differences between carb

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Selenium-Functionalized Molecules (SeFMs) as Potential Drugs and Nutritional Supplements,ed. After the discovery of selenium as a key component of many proteins, significant research efforts have been focused on its therapeutic and nutritional potentials and possible impacts on human and animal health. To date, 25 selenoprotein genes have been identified in humans and animals, where sel

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