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Titlebook: Arterial Chemoreceptors; Mal(adaptive) Respon Sílvia V. Conde,Rodrigo Iturriaga,Emília C. Montei Conference proceedings 2023 The Editor(s)

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https://doi.org/10.1007/978-3-031-51471-5rstanding of the functioning of this stunning germinal niche will very likely facilitate the management and treatment of an important group of diseases that course with carotid body over-activation and malfunction.
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The Adult Carotid Body: A Germinal Niche at the Service of Physiology,rstanding of the functioning of this stunning germinal niche will very likely facilitate the management and treatment of an important group of diseases that course with carotid body over-activation and malfunction.
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The Adult Carotid Body: A Germinal Niche at the Service of Physiology,r the organismal adaptation to a maintained hypoxemia. Profound angiogenic and neurogenic processes take place in the carotid body to facilitate this adaptation process. We have described a plethora of multipotent stem cells and restricted progenitors, from both vascular and neuronal lineages, exist
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Evidences That Sympathetic Overactivity and Neurogenic Hypertension Correlate with Changes in the Rved in some experimental models of hypoxia? Although there is evidence supporting the concept that sympathetic-respiratory coupling is increased in different models of experimental hypoxia [chronic intermittent hypoxia (CIH) and sustained hypoxia (SH)], it was also observed that in some strains of r
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Control of Arterial Hypertension by the AhR Blocker CH-223191: A Chronopharmacological Study in Chruently display a non-dipping pattern of blood pressure (BP) and resistant HTN. After discovering that AHR-CYP1A1 axis is a druggable target in CIH-HTN, we hypothesized that CH-223191 could control BP in both active and inactive periods of the animals, recovering the BP dipping profile in CIH conditi
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,Three Days of Chronic Intermittent Hypoxia Induce β1-Adrenoceptor Dependent Increases in Left VentrWe previously demonstrated that exposure to CIH increases cardiac output and sought to determine if enhanced cardiac contractility manifests prior to hypertension..Male Wistar rats were exposed to cyclical bouts of hypoxia (FiO. = 0.05 nadir; 90 s) and normoxia (FiO. = 0.21; 210 s) 8 h/day for 3 day
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The Beneficial Effect of the Blockade of Stim-Activated TRPC-ORAI Channels on Vascular Remodeling aH). Rats exposed to CIH develop systemic and lung oxidative stress, pulmonary vascular remodeling, and PH and overexpress Stim-activated TRPC-ORAI channels (STOC) in the lung. Previously, we demonstrated that 2-aminoethyl-diphenylborinate (2-APB)-treatment, a STOC-blocker, prevents PH and the overex
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Intermittent Hypoxia and Weight Loss: Insights into the Etiology of the Sleep Apnea Phenotype,omplex disorder remains limited. Because apneas lead to recurrent drops in O. during sleep, intermittent hypoxia (IH) is the main animal model to explore the pathophysiology of SA. Here, we assessed the impacts of IH on metabolic function and related signals. Adult male rats were exposed to 1 week o
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