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Titlebook: Arachidonic Acid Metabolism and Tumor Promotion; Susan M. Fischer,Thomas J. Slaga Book 1985 Martinus Nijhoff Publishing, Boston 1985 Nucle

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发表于 2025-3-21 16:25:28 | 显示全部楼层 |阅读模式
期刊全称Arachidonic Acid Metabolism and Tumor Promotion
影响因子2023Susan M. Fischer,Thomas J. Slaga
视频videohttp://file.papertrans.cn/161/160600/160600.mp4
学科分类Prostaglandins, Leukotrienes, and Cancer
图书封面Titlebook: Arachidonic Acid Metabolism and Tumor Promotion;  Susan M. Fischer,Thomas J. Slaga Book 1985 Martinus Nijhoff Publishing, Boston 1985 Nucle
Pindex Book 1985
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发表于 2025-3-21 23:41:58 | 显示全部楼层
Arachidonic Acid Metabolism in the Skin,ught about by rapid biosynthesis in response to a variety of chemical, physical and hormonal factors. This synthesis or arachldonlc acid cascade is complex and includes several enzymes that are affected by endogenous and/or exogenous regulatory factors. Generally, molecular oxygen is inserted into a
发表于 2025-3-22 02:36:05 | 显示全部楼层
Arachidonic Acid Metabolism and Tumor Promotion, modulatory role in the development of neoplasias. Mouse skin has proved to be one of the best model systems for studying the multistage nature of carcinogenesis (1–3). Skin tumors in mice can be readily induced by the sequential application of a subthreshold dose of a carcinogen (initiation stage)
发表于 2025-3-22 05:34:11 | 显示全部楼层
Prostaglandins, Epidermal Hyperplasia and Skin Tumor Promotion,nated arachidonic acid derivatives such as hydroxy-, hydroperoxy fatty acids and leukotrienes, prostaglandins have been reported as being produced in many tissues (for review see 1,2). Generally, production in a given tissue is initiated by an exogenous or endogenous stimulus and the prostaglandins
发表于 2025-3-22 09:25:39 | 显示全部楼层
发表于 2025-3-22 14:24:24 | 显示全部楼层
Tumor Promoting Phorbol Esters May Affect Cell Membrane Signal Transmission and Arachidonate Metabod influence growth and differentiation of cells in culture (5,6,7,8). These studies have taken a major step forward with the identification and characterization of a receptor protein to which phorbol esters bind. These findings, especially aspects relevant to arachidonate metabolism, are reviewed be
发表于 2025-3-22 18:26:14 | 显示全部楼层
Active Oxygen and Promotion,ms of active oxygen are superoxide (O.) and its conjugate acid the hydroperoxyradical (HO.), singlet oxygen (O.), the hydroxyl radical (.OH) and hydrogenperoxide (H.O.). On the basis of epidemiological considerations, Totter (1) has proposed that oxygen-induced cellular damage rather than exposure t
发表于 2025-3-22 22:51:59 | 显示全部楼层
Possible Involvement of Arachidonate Products in Tumor Promoter Inhibition of Cell-Cell Communicatih the environment via different kinds of feedback or communicating mechanisms (1,2). Unless there is a functional hierarchical organization of the molecular, biochemical, cellular, physiological and psychological (in the case of human beings), this state of health cannot be maintained. Proper geneti
发表于 2025-3-23 03:57:06 | 显示全部楼层
Proteases and Cyclic Nucleotides,function of general protein degradation, they also produce limited proteolysis which converts zymogens to active enzymes by the hydrolysis of a single peptide bond or of several bonds by sequential action. Much work over the past 10–15 years has been directed at the determination of a specific role
发表于 2025-3-23 06:53:16 | 显示全部楼层
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