Titlebook: Apoptosis Techniques and Protocols; Andréa C. LeBlanc Book 2002Latest edition Humana Press 2002

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Basilar-Artery

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Monitoring Caspases in Neuronal Cell Death,ke the proper connections with their postsynaptic targets die naturally during development due to the lack of sufficient trophic support (.). Cell demise is operated in a wellordered fashion and culminates in the activation of a network of specific proteases, the caspases that execute the death prog

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Designing Microarray Experiments for Neurobiology,a powerful method for estimating the behavior of 10,000 genes simultaneously. But how often does it work well? Because of the rapid adoption of this young technology, we have to anticipate that one of the consequences will be the occasional publication of incorrect results. Some microarray data are

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Analysis of Gene Expression by Nylon Membrane cDNA Arrays,g this technology to an issue of potentially high relevance to current research in Alzheimer’s Disease (AD). The AD field is in strong need of biomarkers suitable for the diagnosis of AD prior to symptomology. Amyloid-beta (Aβ) deposition in the brain is a hallmark of AD, and amino acid racemization

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Glyceraldehyde-3-phosphate Dehydrogenase as a Target for Antiapoptotic Drugs,ole in glycolysis. Indeed, the most frequent reference to GAPDH in recent scientific literature is as the “housekeeping” gene used to standardize Northern blots. A careful examination of the literature of the last 25 years, however, reveals a number of novel actions of GAPDH beyond a role in glycoly

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In Situ Detection of Apoptotic Neurons,type of non-necrotic, regulated cell death observed in the nervous system, it is by far the most extensively investigated (.,.). Studies in a variety of species, cell types, and experimental paradigms have led to a better understanding of the molecular pathways that regulate apoptosis and recognitio