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Titlebook: Antitumor Antibiotics; S. K. Carter (Director),Hamao Umezawa (Head),Yoshi Book 1978 Springer-Verlag Berlin · Heidelberg 1978 antibiotics.c

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期刊全称Antitumor Antibiotics
影响因子2023S. K. Carter (Director),Hamao Umezawa (Head),Yoshi
视频video
学科分类Recent Results in Cancer Research
图书封面Titlebook: Antitumor Antibiotics;  S. K. Carter (Director),Hamao Umezawa (Head),Yoshi Book 1978 Springer-Verlag Berlin · Heidelberg 1978 antibiotics.c
影响因子The scientific collaboration between the United States and Japan in the field of cancer goes back many years. In this successful international collaboration cancer chemotherapy has been one of the most productive areas. Pioneers such as YOSHIDA, UMEZAWA, SHEAR, and GOLDIN established firm links of mutual trust and respect in the period after the Second Great War. Japanese drugs, such as mitomycin C and bleomycin have become mainstays of clinical oncology in the U. S. and throughout the world. Many drugs developed in the U. S. have become established in Japanese cancer therapy. Within the cancer chemotherapy field the antitumor antibiotics rank as one of the most important groups. In the U . S. -J apanese collaboration this group of drugs has taken the paramount role. The Japanese, under the leadership of U mezawa, are considered to be among the most innovative and productive in this area which has also had great emphasis in the United States as part of the National Cancer Institute‘s drug development program and in the pharmaceutical industry. This extended collaboration in general oncology, and chemotherapy in particular, has received increased impetus by and support from the offi
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Electronic Commerce und Kundenbindungemphasis on fermentation products. The detailed reports by . in 1957 [1] and . et al in 1966 [3] discussed at considerable length the many factors that influenced the early development of the program. Although it is not possible to discuss those factors in detail here, I will attempt to present some
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Friedhelm Bliemel,Georg Fassottrganisms, their fermentation, screening productivity, antineoplastic structures of interest, and future plans follows..NCI initiated its fermentation program in 1956 and, during the next four years, the primary organisms isolated and screened for their abilities to produce antineoplastic agents were
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Electronic Commerce und Kundenbindung this paper, “Microbial transformations” will refer to reactions catalyzed by microbial enzymes, especially when desired and useful metabolites accumulate in fermentation media. Microbial transformations have tremendous potential for use in the development of new antitumor drugs. Concepts related to
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Rechtliche Aspekte des Electronic Commerceethods have involved a microbial or antimetabolite prescreen [7], or tissue culture cytotoxicity assay systems [6], prior to testing of the culture filtrate in animals. In the program that will be discussed here, all fermented beers are screened initially against the L1210 and KB9 cell lines for cyt
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Friedhelm Bliemel,Georg Fassottiotics in 1953. During the last 15 years, there has been great progress in studies of the mechanisms of cytotoxic actions of antitumor compounds. These studies have shown that antitumor compounds bind or react with DNA, inhibit DNA or RNA synthesis, inhibit protein synthesis, interfere with membrane
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