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Titlebook: Antimutagenesis and Anticarcinogenesis Mechanisms; Delbert M. Shankel,Philip E. Hartman,Gregory Kuny Book 1986 Springer Science+Business M

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The Relation of Activation and Inactivation to Antimutagenic Processeso two parts by Kada (5): desmutagenesis and antimutagenesis per se. Desmutagenesis refers to inactivation of mutagens and carcinogens by whatever means, whether by antioxidants, by cytochrome P-450-associated activity, or by the active destruction or absorption of the toxic substances before they ca
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Cytochromes P-450 and the Activation and Inactivation of Mutagens and Carcinogensydrocarbons, carcinogens, and mutagens, are catalyzed by the cytochrome P-450-dependent drug metabolism system (5). This system is found in the endoplasmic reticulum of various mammalian tissues and organs, e.g., lung, small intestines, etc. (20, 24), but the greatest concentration and activity are
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Isolation and Identification of Higher Plant Agents Active in Antimutagenic Assay Systems: ,r repair the deleterious influence of noxious chemicals in the environment on DNA. Animals tend to defend themselves through the use of enzymes which intercept aggressive chemicals and convert them to less dangerous substances. Animal cells also contain a variety of preformed smaller molecular weigh
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