Titlebook: Antibodies in Cytokines; The concerted action Huub Schellekens Book 1997 Springer Science+Business Media Dordrecht 1997 Antigen.cytokine.di

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thrombus

Interferon antibodies in patients with infectious diseases,ce the early clinical trials it was documented that the therapeutic use of IFNs could be complicated by the development of antibodies able to neutralize or to bind to the IFN molecule..After several years of research it is now widely accepted that the presence of circulating anti-IFN antibodies may

Cirrhosis

Treatment-induced antibodies to interleukin-2,ired immune deficiencies, infectious disorders, and as an adjuvant to vaccines. Both natural and recombinant type IL-2 preparations have been applied in clinical treatment trials and have turned out to be immunogenic, although to a varying extent. Enzyme immunoassays and western blotting are standar

Mutter

OCTO

高尔夫

Anti-cytokine autoantibodies: Epiphenomenon or critical modulators of cytokine action,e, are increased in the circulation of patients subjected to cytokine therapy or suffering from a variety of immunoinflammatory diseases. It has been suggested that these autoantibodies play a regulatory role in the intensity and duration of an immune response. The antibodies may prevent the binding

恸哭

,Potential therapeutic use of antibodies directed towards HuIFN-γ,tion and delayed-type hypersensitivity have indicated that administration of antibodies against IFN-γ can prevent the occurrence of diseases or alleviate disease manifestations. Therefore, it is speculated that such antibodies may have therapeutical efficacy in human diseases. Since animal-derived a

abysmal

Structure-activity of type I interferons,or and transmit signals to cellular nucleus through a similar mechanism, eliciting roughly homogeneous biological activity. Nevertheless, the members of that family, IFNα species, IFNβ and IFNω, due to local differences in the structure sometime show distinct properties. From the reported data it re

Forsake

翅膀拍动

The Expression of Potency of Neutralizing Antibodies for Interferons and other Cytokines,mportance of establishing a common method of reporting neutralizing antibody levels for such cytokines. For quantitative neutralization bioassays, the preferred expression of the neutralizing potency of an antiserum is a titer, that is, the dilution of serum that reduces 10 Laboratory Units (LU)/ml