Titlebook: Antiangiogenic Agents in Cancer Therapy; Beverly A. Teicher Book 19991st edition Springer Science+Business Media New York 1999 angiogenesi

cortex

翅膀拍动

Heinrich Labhart,Edwin Haselbach time thalidomide was withdrawn from the market in 1962, thousands of babies worldwide were estimated to have been born with thalidomide-related defects. As a consequence, the mechanism by which thalidomide causes birth defects has been intensively investigated. Nevertheless, the mechanism has remained elusive .

非实体

Regulation of Angiogenesis by the Organ Microenvironmentstics, such as cell-surface receptors, enzymes, karyotypes, cell morphologies, growth properties, sensitivities to various therapeutic agents, and in the ability to induce angiogenesis, and to invade and produce metastasis .

amputation

Fibroblast Growth Factors in Tumor Progression and Angiogenesisfor the proliferative stimulus in tumors derived from these cells. At the same time, some of the FGFs are mitogenic for endothelial cells, and are capable of promoting tumor angiogenesis. It is therefore difficult to separate the functional role of FGFs in tumorigenesis from their role in tumor angiogenesis.

POINT

Thalidomide and Analogs time thalidomide was withdrawn from the market in 1962, thousands of babies worldwide were estimated to have been born with thalidomide-related defects. As a consequence, the mechanism by which thalidomide causes birth defects has been intensively investigated. Nevertheless, the mechanism has remained elusive .

裂口

white-matter

Role of Inflammatory Mediators in Angiogenesiseptides, pro- and anticoagulants, and fibrinolytic factors), with activities often partially overlapping, represent the “area codes” used to control this network, and can address endothelial cells to assume an inflammatory and/or an angiogenic phenotype ..

方便

Angiogenesis and Oxygen Transport in Solid Tumorss and development of multicellular organisms ., but it occurs only rarely in adult tissues in a tightly controlled manner during normal wound healing and the female reproductive cycle (corpus luteum, placenta, and uterus) .. When these tight controls are breached, the result is unchecked angiogenesi

Melanocytes

Oxygenation of Solid Tumors in Animals and Patientsrgy deposit. This dose modifying role of oxygen (oxygen enhancement ratio) is principally caused by the indirect effect ofradiation on DNA .. Hypoxic cells are present in rodent and xenografted human tumors, and it has been known for a long time that the absence ofoxygen in tumors is a factor ofresi

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