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Titlebook: Anthracycline Antibiotics in Cancer Therapy; Proceedings of the I Franco M. Muggia,Charles W. Young,Stephen K. Carte Conference proceedings

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期刊全称Anthracycline Antibiotics in Cancer Therapy
期刊简称Proceedings of the I
影响因子2023Franco M. Muggia,Charles W. Young,Stephen K. Carte
视频video
学科分类Developments in Oncology
图书封面Titlebook: Anthracycline Antibiotics in Cancer Therapy; Proceedings of the I Franco M. Muggia,Charles W. Young,Stephen K. Carte Conference proceedings
影响因子F. M. MUGGIA When faced with the inadequacies of current cancer treatment, we prefer to look at what the future may hold. Quite often, we take for granted the past, preferring research into totally new areas. However, the persistent development of fertile soil may yield surprising rewards for those who choose to build on the knowledge of the past--hence, this symposium on anthracycline antibiotics. Although the anthracycline antibiotics represent much of the present and future of cancer treatment, their actual use c stretches back barely two decades to the pioneering efforts of Aurelio Di Marco, who characterized the antitumor properties of daunomycin and adriamycin. * The clinical application of these two compounds heralded a decade of excitement among oncologists dealing with pediatric tumors, breast cancer, leukemias, and lymphomas, and opened new hope for patients afflicted with sar­ comas and a variety of other tumors that had been deemed - sistant to chemotherapy. These successes were tempered with the realization that the antitumor effect of anthracyclines could be achieved at times only at the very high price of risking cardiac decompensation and, almost invariably, with th
Pindex Conference proceedings 1982
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978-94-009-7632-0Martinus Nijhoff Publishers, The Hague 1982
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Einführung in die Algebraische Geometriesurvival of cancer patients which modern chemotherapy has made possible. It has been one of the intriguing results of cancer research that many active antineoplastic agents have been found to be carcinogenic. It is now well established that many antitumor substances are oncogenic in cells in culture
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Welche Organellen liegen im Zellplasma?). Exposure of cells in culture to anthracyclines at low concentrations (0.1–10 μM) produces marked inhibition of both DNA and RNA synthesis without appreciable effects on protein synthesis at comparable doses (4–13). In general, preribosomal RNA synthesis is thought to be more sensitive to inhibiti
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