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Titlebook: Anesthesia and Neurotoxicity; Yuji Morimoto Book 2017 Springer Japan 2017 Anesthetics.Neurodegeneration.Neurotoxicity.Postoperative Cognit

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Solidification in an Annular Space,urgery has become an important perioperative clinical issue particularly for geriatric surgical patients. In fact, it has been demonstrated that POCD is associated with increased mortality. Patients suffering from POCD usually complain of deterioration of memory as the initial symptom. Most patients
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https://doi.org/10.1007/978-3-319-45438-2e cost on hospitals. Previous clinical reports revealed that POD appears to be a risk for high mortality in the elderly and POCD appears to have long-lasting adverse effect on learning performance in children. Nevertheless nobody has proposed the effective way to cure them. We are still struggling i
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Simo-Pekka Leino,Susanna Aromaa,Kaj Helin long-term cognitive problems. The mechanisms responsible for POCD/POD are multifactorial and the precise pathogenesis is not well known yet. Tissue injury and systemic insult associated with surgery initiate a systemic reaction accompanied by increased proinflammatory cytokines. These proinflammato
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https://doi.org/10.1007/978-4-431-55624-4Anesthetics; Neurodegeneration; Neurotoxicity; Postoperative Cognitive Dysfunction; Postoperative Deliri
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Laboratory Findings: To What Degree Can We Extrapolate the Animal Data to the Bedside?eloping animals has increased year by year. Thus, it is no exaggeration to say that most anesthetics are neurotoxic to the developing animal brain. The mechanism was first suggested to be neuronal apoptosis, and then abnormality of neurotransmission, especially the manipulation of the GABAergic syst
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Clinical Findings Including Prevention and TreatmentFebruary 2015, the New York Times published an article to inform parents of potential issues with anesthesia use among young children. Parents whose children need surgery are increasingly questioning anesthesiologists regarding this issue. However, associations between anesthesia exposure during inf
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