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Titlebook: An Introduction to Toxicology; Philip C. Burcham Textbook 2014 Springer-Verlag London 2014 Apoptosis.carcinogen.epidemiology.organ.tobacco

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Introduction to Toxicology. is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that “unpack” the concepts being discussed in the text. ​. .978-1-4471-7256-7978-1-4471-5553-9
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The Emergence of Modern Toxicology, than the thalidomide disaster of the early 1960s. A flurry of activity saw toxicology-focussed societies, journals, regulatory agencies and research institutions established around the world. Toxicology today is a highly evolved, multidisciplinary endeavour that develops its own conceptual framewor
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Toxicokinetics: The Behaviour of Chemicals in the Body,s – in controlling the disposition of ingested chemicals. The possibility that one chemical might alter the ability of these proteins to metabolise or export another xenobiotic is also briefly considered (i.e. toxicant interactions).
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Everyday Toxicology II: Tobacco,NNN and NNK undergo CYP-catalysed bioactivation to DNA-damaging metabolites. DNA adducts formed by these and other noxious metabolites drive the accumulation of mutations in growth regulatory genes within the smokers’ lung.
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The Emergence of Modern Toxicology,sed toxic plants and metals for therapeutic purposes as well as ‘professional poisoners’ who offered their services to political leaders for the elimination of unwanted rivals. Eventually, the emergence of modern chemistry began unleashing the economic and scientific powers of chemical substances, a
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Core Concepts in Toxicology,eeded for the types of substances that are of concern to toxicologists, this chapter explores linguistic nuances surrounding such words as poison, toxin, xenobiotic, endobiotic and toxicant. Next, the complications that can accompany study of toxicity due to differences in the duration of chemical e
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