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Titlebook: Alternatives for Dermal Toxicity Testing; Chantra Eskes,Erwin van Vliet,Howard I. Maibach Book 2017 Springer International Publishing AG 2

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Assessment of the Human Epidermis SkinEthic™ RHE Model for , Skin Corrosion Testing of ChemicalsD reference chemicals as recommended in the OECD TG 431, the subcategorization accuracy (i.e. predictive capacity) achieved was 70.8%. Furthermore, due to its high sensitivity and the negligible under-classification, the test method provides high safety standards for skin corrosion testing.
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Book 2017sses areas that may be of relevance for the future of dermal toxicity safety testing, including the validation and regulatory acceptance of integrated testing strategies, novel complex skin models, and high-throughput screening techniques.
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Book 2017ry, and academic use and also explores potential future developments. It encompasses all areas of dermal toxicity, including skin irritation, skin corrosion, skin sensitization, UV-induced effects, and skin genotoxicity. An individual chapter is devoted to each test method, with coverage of the scie
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https://doi.org/10.1007/978-3-8349-9707-4ghting the importance of an optimized rinsing operation for the removal of exposed chemicals in obtaining consistent results from . skin irritation assays. The LabCyte EPI-MODEL24 is included in OECD TG 439 . skin irritation: reconstructed human epidermis test method, which also provides information
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