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Titlebook: Alagille Syndrome; Pathogenesis and Cli Binita M. Kamath,Kathleen M. Loomes Book 2018 Springer International Publishing AG, part of Springe

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Peiming Dong,Ke Zhong,Sixiong Zhao, and our improved understanding of endogenous reparative mechanisms. These putative therapeutic possibilities hold great potential for Alagille syndrome and are also highly translatable to other disease states in which the liver or heart is compromised.
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,Bile Duct Development and the Notch Signaling Pathway,icate, arborizing, hierarchical network of ducts that navigate the liver parenchyma, contributing to liver health and disease not only via drainage of bile but via direct and indirect interactions with surrounding cells. Development of the intrahepatic bile ducts depends upon cell specification and
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Liver Disease in Alagille Syndrome,commonly presents in the neonatal period during evaluation for cholestasis with elevated bilirubin and GGT. The classic finding on liver biopsy is bile duct paucity; however, this is not diagnostic and not all children with Alagille syndrome have paucity on liver biopsy. There are specific clinical
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