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Titlebook: Aging in Cell and Tissue Culture; Proceedings of a sym Emma Holečková,Vincent J. Cristofalo (Associate Me Conference proceedings 1970 Plenu

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Cell Strain Senescence in Vitro: Cell Culture Anomaly or an Expression of a Fundamental Inability oroperties and morphology which take place with continued passage. Swim and associates [1, 2] clearly defined the characteristics of two distinct classes of cells which proliferate in vitro. One class, later termed primary cell lines by Harris [3] and others, comprises the apparently unaltered progen
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A Theoretical and Experimental Approach to the Relationship Between Cell Variability and Aging in V limited lifetime should reflect aging in vivo [1]. In contrast to the senescence theory an environmental theory has also been proposed, stating that conditions in vitro are insufficient for sustaining cell growth indefinitely.
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Metabolic Aspects of Aging in Diploid Human Cells,independent of the environment exists at the cellular level and operates in such a manner that senescence and death are the programmed destiny of normal mammalian cells and tissues. A model system which allows an approach to some aspects of this question is provided by the diploid human cell lines [
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A 72-Year-Old Woman with a Diffuse Erythema, Scaling on the Scalp and Coexisting Hair Loss, fungoides is mainly patchy (84%). However, alopecia totalis or universalis may occur. In same patients, areas of hair loss with normal skin or mild erythema and scaling is observed. In others, hair loss is associated with patchy, plaque or follicular lesions. Diagnosis of mycosis fungoides requires
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