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Titlebook: Aggressive Lymphomas; Georg Lenz,Gilles Salles Book 2019 Springer Nature Switzerland AG 2019 Malignant Lymphoma.Therapy Malignant Lymphoma

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Standard of Care Relapsed DLBCLD20 monoclonal antibody rituximab (R) to conventional chemotherapy has dramatically improved event-free survival (EFS) and overall survival (OS) in DLBCL [3], a significant proportion of patients are refractory or relapse following first-line treatment.
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Burkitt Lymphomaase has been challenging. While the central role of . in BL has been appreciated for some time, recently, several new mutations that cooperate with . and have critical roles in lymphomagenesis have been identified. This potentially paves the way for novel drug development in this disease. Treatment-
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Extranodal Localization of Aggressive Lymphomazed by distinct biology, clinical presentation, and treatment considerations. Though any extranodal site in the body may be involved by DLBCL, unique consideration is warranted for DLBCLs which primarily involve the GI tract, bone, mediastinum, testis, breast, and skin. These entities will be review
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Role of Modern Imaging with FDG-PET/CT in Aggressive Lymphomaturing both anatomic and metabolic information with combined PET-CT. The poorer prognosis of patients who fail to obtain a complete metabolic response after rituximab-chemotherapy has driven interim PET-CT assessment applying the 5-point scale or measuring changes in the standardised uptake value (Δ
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Kinase Inhibitors in Large Cell Lymphomamultistep signaling pathways. Phosphorylation is directed through hundreds of specific kinases which can be activated through a variety of mechanisms. Not surprisingly, these tightly regulated networks are critical to nearly all cellular functions and can be abnormally activated or suppressed in can
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