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Titlebook: Advances in Tracer Methodology; Volume 1 Seymour Rothchild Book 1963 Springer Science+Business Media New York 1963 Atom.combustion.informat

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发表于 2025-3-21 18:00:44 | 显示全部楼层 |阅读模式
期刊全称Advances in Tracer Methodology
期刊简称Volume 1
影响因子2023Seymour Rothchild
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图书封面Titlebook: Advances in Tracer Methodology; Volume 1 Seymour Rothchild Book 1963 Springer Science+Business Media New York 1963 Atom.combustion.informat
影响因子The five Symposia on Advances in Tracer Methodology were held annually from 1957 to 1961. The symposia were directed to scientists who are active in utilizing tracer techniques to help solve their scientific problems. The format, an informal one-day meeting consisting of about ten papers and closing with a cocktail hour, fostered an active exchange of information among speakers and audience. Although the first two symposia were restricted to the use of tritium as a tracer isotope, the larger purpose of the meetings was to disseminate information relating to the entire isotopic tracer field. The sponsoring organizations, all actively engaged in selling products in the nuclear field, attempted to provide a noncom­ mercialized forum which would facilitate this exchange of in­ formation. The collection of papers presented herein represents most of the talks presented at the first symposia plus several appropriate papers which have appeared either in Atomlight, the bulletin of the New England Nuclear Corp., or which have been submitted directly for inclusion in this collection. Although each of the authors was given the opportunity to revise his paper, it is likely that some of the tech
Pindex Book 1963
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Experiences with Tritiated Compounds Prepared by Exposure to Tritium Gaspounds. Despite the absence of an adequate theory for predicting the specific activity attainable with a particular substance, the method has proven successful in labeling a great variety of compounds, including biologically active materials such as ribonucleic acid, lysozyme [2], and insulin [3]. I
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Tritium Gas Exposure Labelingritium labeling. Experience has confirmed the initial report that activities in the range of 1–100 mc/g are generally obtained by exposure to curie amounts of tritium for several days, and that labeling is accompanied by the formation of tritiated by-products of high specific activity. Information o
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Some Experiences with Labeling Nucleotides. This observation followed largely from the initial work of Leloir and his collaborators [1] and of Park [2]. Work by Cifonelli and Dorfman [3] showed that Group A streptococci contain UDP-glucuronic acid (UDPGA), UDP-N-acetylglucosamine (UDPAG), and UDP-N-acetylmuramic acid. The first two, UDPGA a
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Tritium Labeling by Other Methodsables one to obtain considerably higher specific activities and specifically labeled positions. Thus, the tritium gas exposure method of labeling should be considered only after other synthetic routes have been eliminated or if a randomly labeled molecule is required.
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Preparation of Tritium-Labeled Paromomycin (Humatin) by Fermentation in a Medium Containing Tritiaten radiochemically pure paromomycin following exposure to tritium gas by the Wilzbach technique [2] prompted us to try biosynthesis. While biosynthetic incorporation of hydrogen isotope from water into organic compounds has been reported frequently in the literature [3–5], this technique has not been
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