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Titlebook: Adjuvant Therapy of Primary Breast Cancer; Hans-Jörg Senn,Aron Goldhirsch,Bruno Osterwalder Conference proceedings 1989 Springer-Verlag Be

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Dirichlet and Polya tree process,subsequent course (Kurtz et al. 1988 a). The purpose of this paper is to analyze the development of breast recurrence as a function of time, as well as to study the prognosis following treatment of local failure.
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Inference for Location Parameter,n of patients whose tumors are more responsive to a given treatment (e.g. patients with estrogen-receptor(ER)-positive tumors, who are receiving adjuvant endocrine therapy) (Ludwig Breast Cancer Study Group 1984). The use of sequential non-cross-resistant combinations also appears to enhance effectiveness (Perloff et al. 1986).
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Dirichlet and Polya tree process,reasing doses through a multilog cell kill model. In this regard, the alkylating agents more closely resemble radiotherapy. The lack of cross-resistance among the alkylating agents in both in vitro and in vivo models has important implications for clinical treatment strategies (Frei et al. 1985; Frei et al., in press; Teicher et al. 1986).
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0080-0015 in this disease, the benefits of therapy are relatively mod­ est, the availability and interpretation of the data from trials be­ comes an issue of primary importance. The effects of present treat­ ment are in fact such that more patients relapse despite therapy than are estimated to benefit from i
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Inference for Location Parameter,research. There is no question that such a development, if proven correct, will result in very significant practical alterations of the orthodox management of breast cancer. Therefore, before its full implementation, rigorous testing in clinical trials will be required.
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