Overview: This two-part volume is an update and objective state of the art of the current knowledge in the field, with particular emphasis on the development of novel therapeutic entities that may prove useful Physiological, pharmacological and molecular biological data generated over the past three decades have demonstrated the existence of two major families of extracellular receptors, the P1, a family of four G-protein coupled receptors and the P2, a family of at least 12 receptors responsive to purine (ATP, ADP) and pyrimidine (UTP) nucleotides through which adenosine and ATP can function
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