lymphedema
发表于 2025-3-28 16:25:31
Optimized Protocols for siRNA Delivery into Monocytes and Dendritic Cells,ation, function, and survival can be modulated by small interfering RNAs (siRNAs) targeting genes involved in immune suppression. This chapter describes detailed protocols for introducing siRNAs into human monocytes and dendritic cells using standard electroporation techniques.
拒绝
发表于 2025-3-28 21:24:19
Inhibition of the microRNA Pathway in Zebrafish by siRNA,this important vertebrate model because of unspecific developmental defects. We have recently shown that these side effects can be attributed to inhibition of the miRNA pathway by siRNAs at early embryonic stages. This review highlights these findings and the function of microRNAs in zebrafish development.
admission
发表于 2025-3-29 02:16:22
RNA Modifications: A Mechanism that Modulates Gene Expression,and protein translation are two major steps in eukaryotic gene expression that necessitate the production of accurate gene products. Both processes occur in large complexes, consisting of both proteins and noncoding RNAs. Interestingly, the RNA components contain a large number of posttranscriptiona
expository
发表于 2025-3-29 06:31:40
Quantitative Analysis of RNA Modifications, modifications impact cellular processes necessitates the ability to both detect and quantify the presence of these modifications within RNA molecules. Here, we present a detailed procedure that allows the detection and quantification of RNA base modifications. This procedure involves a number of te
纵火
发表于 2025-3-29 07:27:41
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诽谤
发表于 2025-3-29 14:12:23
Progress in siRNA Delivery Using Multifunctional Nanoparticles,icles need to efficiently encapsulate siRNA, actively target sites of interest, and release siRNA intracellularly. This chapter reviews recent progress using a multifunctional approach to design and engineer polymeric nanoparticles for siRNA delivery.
膝盖
发表于 2025-3-29 17:37:38
Optimized Protocols for siRNA Delivery into Monocytes and Dendritic Cells, Unfortunately, its curative potential is in general limited by immunosuppressive proteins that negatively regulate dendritic (DC) and/or T-cell function. The recent discovery of RNA interference (RNAi) has facilitated the study of gene function in immune cells and recent data indicate that DC matur
放肆的你
发表于 2025-3-29 21:43:50
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逢迎春日
发表于 2025-3-30 02:12:26
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变白
发表于 2025-3-30 07:21:46
Using OligoWalk to Identify Efficient siRNA Sequences,ression of specific mRNAs. In practice, a number of factors influence whether an siRNA sequence will elicit RNAi and knockdown target gene expression. One factor that significantly influences the efficiency of an siRNA is the effect of RNA secondary structure. Self-structure in either the siRNA sequ