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发表于 2025-3-21 17:58:08
书目名称Optimization in Drug Discovery影响因子(影响力)<br> http://figure.impactfactor.cn/if/?ISSN=BK0703246<br><br> <br><br>书目名称Optimization in Drug Discovery影响因子(影响力)学科排名<br> http://figure.impactfactor.cn/ifr/?ISSN=BK0703246<br><br> <br><br>书目名称Optimization in Drug Discovery网络公开度<br> http://figure.impactfactor.cn/at/?ISSN=BK0703246<br><br> <br><br>书目名称Optimization in Drug Discovery网络公开度学科排名<br> http://figure.impactfactor.cn/atr/?ISSN=BK0703246<br><br> <br><br>书目名称Optimization in Drug Discovery被引频次<br> http://figure.impactfactor.cn/tc/?ISSN=BK0703246<br><br> <br><br>书目名称Optimization in Drug Discovery被引频次学科排名<br> http://figure.impactfactor.cn/tcr/?ISSN=BK0703246<br><br> <br><br>书目名称Optimization in Drug Discovery年度引用<br> http://figure.impactfactor.cn/ii/?ISSN=BK0703246<br><br> <br><br>书目名称Optimization in Drug Discovery年度引用学科排名<br> http://figure.impactfactor.cn/iir/?ISSN=BK0703246<br><br> <br><br>书目名称Optimization in Drug Discovery读者反馈<br> http://figure.impactfactor.cn/5y/?ISSN=BK0703246<br><br> <br><br>书目名称Optimization in Drug Discovery读者反馈学科排名<br> http://figure.impactfactor.cn/5yr/?ISSN=BK0703246<br><br> <br><br>
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发表于 2025-3-21 23:18:28
Use of Caco-2 Cell Monolayers to Study Drug Absorption and Metabolism,nd dietary chemicals. The Food and Drug Administration (FDA) recognized the model system as useful in classifying a compound’s absorption characteristics in the Biopharmaceutics Classification System. In addition to its usefulness as an absorption model, the Caco-2 cells are useful for studying the
antecedence
发表于 2025-3-22 02:24:50
Absorption Screening Using the PAMPA Approach,earliest absorption, distribution, metabolism, and excretion (ADME) primary screening of research compounds. PAMPA’s popularity in the industry has risen rapidly. This chapter focuses on state-of-the-art PAMPA methods. Evidence will be cited demonstrating that as far as predicting passive permeabili
星球的光亮度
发表于 2025-3-22 07:44:09
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Capture
发表于 2025-3-22 09:36:42
In Vitro Permeation Study With Bovine Brain Microvessel Endothelial Cells, lines such as Caco-2, MDCK, MDCKII, and LLC-PK have been used to predict in vivo intestinal absorption of drugs. However, there are no well-characterized cell lines available representing the blood-brain barrier. In this chapter, the authors describe the primary culture of bovine brain microvessel
植物群
发表于 2025-3-22 13:40:12
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amorphous
发表于 2025-3-22 20:08:49
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大笑
发表于 2025-3-22 22:09:10
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Ablation
发表于 2025-3-23 01:45:40
Isothermal Titration Calorimetry Characterization of Drug-Binding Energetics to Blood Proteins,les. In this chapter, the authors describe the use of isothermal titration calorimetry (ITC) to measure the binding energetics of drugs bound to blood proteins (i.e., human serum albumin and α-acid glycoprotein ). The stoichiometry (.), the association-binding constant (..), and the entha
噱头
发表于 2025-3-23 06:50:22
Metabolic Stability Assessed by Liver Microsomes and Hepatocytes,c stability assays, the typical test systems are liver microsomes, liver S9, or hepatocytes (plated or suspended), depending on the goal of the assay. To determine the metabolic stability of a new chemical entity, quantification of the drug candidate from incubate supernatants is required and usuall