Conjuction 发表于 2025-3-28 16:24:29
Zhengyin Yan,Gary W. CaldwellIncludes supplementary material:Exclaim 发表于 2025-3-28 22:16:15
Optimization in Drug Discovery978-1-59259-800-7Series ISSN 1557-2153 Series E-ISSN 1940-6053云状 发表于 2025-3-29 02:32:42
http://reply.papertrans.cn/71/7033/703246/703246_43.pngmicronutrients 发表于 2025-3-29 06:27:10
http://reply.papertrans.cn/71/7033/703246/703246_44.pngProclaim 发表于 2025-3-29 09:40:33
Absorption Screening Using the PAMPA Approach,s chapter also discusses how PAMPA has relevance in preformulation research. A detailed PAMPA protocol is presented, with step-by-step instructions for a popular version of the assay, using relatively inexpensive and readily obtainable components.意外 发表于 2025-3-29 14:58:33
An Enzymatic Microplate Assay for Testing P-Glycoprotein Substrates and Inhibitors,erapamil, vinblastine, and progesterone) in addition to its basal ATPase activity. This assay uses a coupled enzyme system with spectrophotometric detection for measurement on P-gp-containing native membrane vesicles. This assay may be performed on 96- or 384-well microplates and is therefore suitable for high-throughput screenings.虚度 发表于 2025-3-29 19:25:04
http://reply.papertrans.cn/71/7033/703246/703246_47.png放大 发表于 2025-3-29 22:51:10
http://reply.papertrans.cn/71/7033/703246/703246_48.png彻底明白 发表于 2025-3-30 03:09:06
http://reply.papertrans.cn/71/7033/703246/703246_49.png到婚嫁年龄 发表于 2025-3-30 07:46:36
In Vitro CYP Induction in Human Hepatocytes, nontransplantable human liver followed by their culture and treatment with new chemical entities and/or known inducers of cytochrome P450. Enzyme induction in cultured human hepatocytes can be assessed by measuring the levels of messenger ribonucleic acid, immunoreactive protein, and/or cytochrome P450 enzyme activity as outlined in this chapter.