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Jeremy Kilpatrick,Celia Hoyles,Ole Skovsmose,Paola Valero expertsThis detailed volume provides a robust set of methods to understand variation between patients with ovarian cancers, in vitro models to better study different stages of the disease, and in vivo models to test therapies. Beginning with clinical perspectives to orient basic scientists, the boo使入迷 发表于 2025-3-22 05:48:56
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Maria G. Bartolini Bussice detection, have accommodated a dramatic increase in the versatility of optical trapping. Quadruple (Q)-trap optical tweezers are an excellent example of such an advance, by providing three-dimensional control over two constructs and thereby enabling for example DNA-DNA braiding. However, the impl向下 发表于 2025-3-22 14:52:26
Rolf Biehleringle-stranded (ss)DNA. Yet assembly of the required substrates, which often contain a ssDNA segment embedded within a larger double-stranded (ds)DNA construct, can be time-consuming and inefficient, particularly when using a standard three-way hybridization protocol. In this chapter, we detail howALLEY 发表于 2025-3-22 17:56:51
Ole Skovsmosey convert the duplex form of nucleic acids to single-stranded intermediates for many biological processes. These enzymes play vital roles in nearly all aspects of nucleic acid metabolism, such as DNA repair and RNA splicing. Understanding helicase’s functional roles requires methods to dissect the mneutral-posture 发表于 2025-3-22 22:24:03
Jeremy Kilpatrick,Celia Hoyles,Ole Skovsmose,Paola Valeroxhibit complex conformation and stoichiometry changes in coordination with their motion and activity. To further our understanding of the complex machinery of life, we need methods that can simultaneously probe more than one degree of freedom of single molecules and complexes. .uorescence optical twAbbreviate 发表于 2025-3-23 01:28:21
Christine Keitel,Jeremy Kilpatrick expertsThis fully revised new edition explores advances in the prevention and treatment of oral diseases. Beyond the updated chapters, the book delves into regenerative biology, gene editing and the use of CRISPR in oral biology, as well as histone acetylation and deacetylation methods, further refatrophy 发表于 2025-3-23 08:59:14
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