征兵 发表于 2025-3-27 00:35:05
Cos-Seq: A High-Throughput Gain-of-Function Screen for Drug Resistance Studies in ,to improve knowledge about the mode of action of current drugs and those in development, as well as to understand the mechanisms pertaining to their resistance, we recently described a sensitive and high-throughput method termed Cos-Seq. Here we provide a detailed protocol for every step of the proc商议 发表于 2025-3-27 02:12:47
Gene Replacement by Homologous Recombination,that prove to be poor targets for CRISPR/cas-based approaches. Homologous recombination has proven to be relatively robust to minor sequence mismatches between GOI-flanking sequences and the gene replacement constructs, and the faithfulness of recombination events is easily verified by whole-genomeadhesive 发表于 2025-3-27 05:16:51
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Quantification of , Parasites in Murine Models of Visceral Infection,odels of visceral infection lack the clinicopathological aspects of VL in humans, they have been proven useful at advancing our knowledge in the . field. Indeed, these models have been used not only to better understand the pathophysiology of the infection but also in drug and vaccine development. T