鸟场
发表于 2025-3-21 19:50:08
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缺乏
发表于 2025-3-21 22:01:51
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错事
发表于 2025-3-22 02:31:20
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LAIR
发表于 2025-3-22 05:06:51
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condone
发表于 2025-3-22 10:05:45
Adamo D. Rombolà,Massimo Tagliaviniing substrate will frequently help to identify whether the substrate binds as an inhibitor to the same enzyme form as does the noninhibiting substrate, upstream to it, or downstream from it..Determination of the product-inhibition patterns of the reaction in the opposite direction will help further
有毒
发表于 2025-3-22 12:57:17
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弯曲道理
发表于 2025-3-22 17:45:20
Juan J. Lucenaing substrate will frequently help to identify whether the substrate binds as an inhibitor to the same enzyme form as does the noninhibiting substrate, upstream to it, or downstream from it..Determination of the product-inhibition patterns of the reaction in the opposite direction will help further
盟军
发表于 2025-3-22 22:45:39
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推测
发表于 2025-3-23 01:44:26
Zeno Varanini,Roberto Pintonubstrate and inhibitor “probes” provides the prospect for more reliable reaction phenotyping and assessment of drug–drug interaction potential. Although extrapolation of the in vitro intrinsic clearance of a glucuronidated drug often underpredicts in vivo clearance, careful selection of in vitro exp
HAVOC
发表于 2025-3-23 09:16:46
David E. Crowley. The second is sequential metabolism, in other words, the formation of multiple products from one CYP enzyme. Given the degree of CYP enzyme promiscuity, it is hardly surprising that there is also a high degree of complex kinetic profiles generated during the catalytic cycle.