长矛
发表于 2025-3-28 16:26:48
cAMP- and cGMP-dependent control of lipolysis and lipid mobilization in humans: putative targets foipolysis, the hydrolysis of fat cell triacylglycerols by hormone-sensitive lipase (HSL), promotes the release of NEFA and glycerol by fat cells. HSL regulation is under the potent control of cAMP and the cAMP-dependent protein kinase, protein kinase A (PKA). In human fat cells, adenylyl cyclase acti
口诀
发表于 2025-3-28 22:08:13
http://reply.papertrans.cn/47/4679/467846/467846_42.png
分开如此和谐
发表于 2025-3-29 02:10:15
Targeting regulators of G protein signaling (RGS proteins) to enhance agonist specificity,eactivation. Thus they negatively regulate signal transduction mediated by Gi- and Gq-coupled receptors. RGS proteins exhibit both tonic and regulated inhibition of agonist responses, differentially controlling the sensitivity of tissues depending on their post-translational modifications and expres
品尝你的人
发表于 2025-3-29 06:38:38
Dimeric GPCRs: what did we learn from the metabotropic glutamate receptors?,mounts of data support the idea that GPCRs can form dimers, either homodimers or heterodimers (Bouvier 2001). Such an observation has raised a number of important issues concerning the activation process: what is the stoichiometry required for the dimer activation? Is one agonist per dimer sufficien