短暂
发表于 2025-3-21 18:03:51
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COWER
发表于 2025-3-21 21:05:14
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恃强凌弱
发表于 2025-3-22 00:29:11
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短程旅游
发表于 2025-3-22 08:04:59
https://doi.org/10.1007/978-3-031-14406-6ase. Defects in RNA splicing account for at least 10% of all genetic disorders, with the number expected to increase as more information is uncovered on the contribution of noncoding genomic regions to disease. Splice modulation through the use of antisense oligonucleotides (AOs) has emerged as a pr
MUT
发表于 2025-3-22 11:45:42
Giordano Zambelli,Luciano Morgantiproach uses antisense oligonucleotides (AON) to modify the splicing of pre-mRNA to correct the mutation responsible for a disease, or to suppress a particular gene expression, as in allergic diseases. Antisense-mediated exon skipping is most extensively studied in Duchenne muscular dystrophy (DMD) a
multiply
发表于 2025-3-22 15:05:57
Ultrasound, Embodiment and Abortion,tein. Insufficient levels of SMN results in the loss of motor neurons, which causes muscle weakness, respiratory distress, and paralysis. A nearly identical gene (.) contains a C-to-T transition which excludes exon 7 from 90% of the mature mRNA transcripts, leading to unstable proteins which are tar
multiply
发表于 2025-3-22 21:08:21
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mercenary
发表于 2025-3-22 23:24:21
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创新
发表于 2025-3-23 01:25:10
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Critical
发表于 2025-3-23 07:06:01
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