CHAFE 发表于 2025-3-26 22:30:20
Book 2006mulates red blood cell production, in recent years many laboratories have shown that EPO can act as a neuroprotective compound in a variety of injury paradigms in the nervous system. Past experience with relatively safety profile of this FDA-approved drug makes it an ideal candidate to take it into惰性气体 发表于 2025-3-27 01:15:54
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Expression of Erythropoietin and Its Receptor in the Central Nervous System, way to the bone marrow where it regulates red cell production by preventing apoptosis of erythroid progenitor cells. Recently, EPO has emerged as a multifunctional growth factor that plays a significant role in the nervous system. Both EPO and its receptor are expressed throughout the brain in gliaCRAFT 发表于 2025-3-27 18:43:34
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Regulation of Erythropoietin Expression in the Nervous System: The Hypoxia Inducible Factor,) is a physiological response to hypoxia in oxygen-deprived tissues. Hypoxia-induced epo gene expression is regulated by the transcriptional activator hypoxia inducible factor (HIF). The epo gene contains a HIF binding site in its 3′ untranslated region, and its expression is upregulated concomitant人类 发表于 2025-3-28 04:59:10
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Erythropoietin Neuroprotection in the Retina,ursors in the bone marrow. EPO and EPO receptor protein are also expressed by CNS neurons and glial cells. EPO exerts neuroprotective effects in various experimental in vitro and in vivo models of neural injury, such as mechanical trauma, neuroinflammation, and cerebral and retinal ischemia. In this