Gentry 发表于 2025-3-28 18:39:45
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Erythropoietin and Neuroprotection in the Peripheral Nervous System: , Studies,can cross the blood brain barrier and inhibit neuronal death and inflammatory infiltrates induced by ischemia in the brain. Recent evidence also suggests that rhEPO is a potent neuroprotective agent in primary sensory neurons and peripheral glia involved in pain transmission. When L5 spinal nerve isvector 发表于 2025-3-29 05:38:42
,An Endogenous Pathway Preventing Axonal Degeneration Mediated by Schwann Cell — Derived Erythropoieneration and neuronal death are likely to be diverse. In this chapter, we describe a novel, endogenous pathway that prevents axonal degeneration. We show that in response to axonal injury, peri-axonal Schwann cells release erythropoietin (EPO), which via binding to EPO receptors on neurons preventsmeritorious 发表于 2025-3-29 10:40:22
Role of Erythropoietin in Inflammatory Pathologies of the CNS,panied by an inflammatory reaction including production of inflammatory cytokines, leukocyte infiltration, and astroglial activation/ proliferation. In models of middle cerebral artery occlusion, EPO decreases production of tumor necrosis factor (TNF), interleukin (IL)-6, and of monocyte chemoattracinsincerity 发表于 2025-3-29 13:46:35
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Book 2006ifferent disciplines of neuroscience to review the current state-of-the-art in EPO and the nervous system. This book will benefit scientists and clinicians interested in neuroprotection in the broadest sense..CURL 发表于 2025-3-29 22:51:15
,A Review of China’s Economy in 2013, responses. Thus, hypoxically upregulated EPO is a naturally self-regulated physiological protective mechanism in the mammalian brain, especially during ischemia. As EPO is also a clinically extremely well studied and tolerated compound, its use in stroke patients is tempting.Defense 发表于 2025-3-30 00:51:23
https://doi.org/10.1007/978-981-19-8536-2sensing mechanism that regulates the activation of HIF under hypoxic conditions. An important challenge for the future is to determine how modulating the activation of HIF with the subsequent expression of EPO can be beneficial for neural survival under stress conditions that involve hypoxia.ensemble 发表于 2025-3-30 07:14:59
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