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Elaine Clanton Harpine,Adam Pazdapeptides. Reactions are irreversible and proceed with unprotected peptides (μM–mM concentration) in aqueous solution at slightly basic pH. Due to its high catalytic efficiency, only very low molar equivalents of omniligase-1 are required. In this chapter, a chemoenzymatic peptide synthesis (CEPS) ap绑架 发表于 2025-3-30 18:04:17
https://doi.org/10.1007/978-3-319-59141-4directly from nature of introducing a unique amino acid into the larger context of a protein. Formylglycine (fGly) is a crucial component of the active site of sulfatases, where it directly participates in the breakdown of sulfate ester substrates. In the context of bioconjugation this aldehyde cont颂扬国家 发表于 2025-3-30 21:35:29
https://doi.org/10.1007/978-3-319-59132-2Asx) ligase activity and is virtually devoid of protease activity. Butelase 1 recognizes specifically a .-terminal Asx-containing tripeptide motif, Asx-His-Val, to form an Asx-Xaa peptide bond (Xaa = any amino acid), either intramolecularly or intermolecularly, resulting in cyclic peptides or site-saspect 发表于 2025-3-31 02:27:23
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